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Diet drug Meridia pulled off market

Abbott Laboratories on Friday pulled it's diet drug Meridia off the market in the US at the request of the Food and Drug Administration because the medicaiton increases the risk of heart attacks and strokes.

“Meridia’s continued availability is not justified when you compare the very modest weight loss that people achieve on this drug to their risk of heart attack or stroke,” said John Jenkins, director of the the FDA’s office of new drugs in the Center for Drug Evaluation and Research. “Physicians are advised to stop prescribing Meridia to their patients and patients should stop taking this medication. Patients should talk to their health care provider about alternative weight loss and weight loss maintenance programs.”

Earlier Friday the Canadian health department announced that Abbott had agreed to pull Meridia from the market in that country due the risk of cardiovascular events such as strokes and heart attacks, according to the Associated Press. The AP added that “European regulators withdrew the drug in January."

Also Friday, the FDA advised people who use the “herbal” product Slimming Beauty Bitter Orange Slimming Capsules to immediately stop taking the pills because they contain sibutramine, the active ingredient in Meridia. Sibutramine is a stimulant.

The FDA’s Slimming Beauty warning stated:

“Consumers who are otherwise healthy and who take the amount of sibutramine found in Slimming Beauty capsules can experience anxiety, nausea, heart palpitations, a racing heart, insomnia, and elevated blood pressure. Sibutramine also may interact with other medications and can cause serious side effects. Sibutramine is a powerful stimulant that should not be used without a prescription due to the safety risks associated with it.”

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FDA: GSK seizure drug linked to meningitis

Concerned by a string of reports over the past 16 years that the anti-seizure drug Lamictal can cause aseptic meningitis in rare instances, the FDA has flagged their concerns to physicians and plans to revise the label with GlaxoSmithKline

"Aseptic meningitis is a rare but serious side effect of Lamictal use," says Russell Katz, director of the Division of Neurology Products in the FDA's Center for Drug Evaluation and Research. "Patients that experience symptoms should consult their health care professional immediately."

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Glaxo Settles Some Paxil Lawsuits

GlaxoSmithKline PLC said Tuesday it has settled certain lawsuits alleging its Paxil antidepressant caused birth defects in some users but didn't give financial details.

The U.K.'s biggest drug company said in an email it "has reached agreement to settle certain cases involving the use of Paxil during pregnancy. The details of those settlements are confidential. Other cases remain pending."

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Accutane Lawsuits Raise Questions about Efficacy of Drug Warning Labels

The recent decision of a New Jersey appeals court to overturn a $10.5 million Accutane lawsuit verdict has drawn attention to the ongoing debate over the effectiveness of drug warning labels.

The reversal is the latest development in a lawsuit filed by Kamie Kendall, who first began taking Accutane in 1997 when she was 13 years old. By the time she was 15, she began experiencing bloody diarrhea and other abnormal gastrointestinal symptoms, which continued for years and eventually led to the surgical removal of her colon.

The crux of Kendall's argument against Roche Pharmaceuticals, the manufacturer of Accutane, was that the company did not do enough to warn her of the risks of severe gastrointestinal problems associated with the medication. Even though Accutane's information label contained a warning that the medication may increase the risk of severe conditions such as inflammatory bowel disease, Kendall claimed the warning was buried in a label that gave more attention to other potential side effects such as birth defects and suicide.

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HPV linked to head, neck cancers - Chicago Tribune

A virus known to cause cervical cancer in women is increasingly being identified in head and neck cancers, leading to suspicion that the route of infection may be oral sex. Human papillomavirus, or HPV, is ...
   
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FDA Recalls

Food and Drug Administration--Recalls/Safety Alerts