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Seroquel

Seroquel (quetiapine), manufactured by Astra Zeneca, is an atypical antipsychotic medication in the chemical class called dibenzothiazepine derivatives. Seroquel was approved for the treatment of schizophrenia and affects a broad range of neurotransmitter receptors, including serotonin receptors. Seroquel was approved by the FDA for marketing in 1997. Although its approval was limited to the treatment of schizophrenia, in 1999 the FDA warned Astra Zeneca about its claim in materials distributed since its original approval that the drug is useful in the treatment of bipolar and schizaffective disorders.

Like other atypical antipsychotic drugs in its class (dibenzothioazepines), Seroquel has been linked to a higher incidence of diabetes. Data from a recent medical conference in Philadelphia showed patients on Seroquel had 3.34 times as many cases of diabetes as those on older drugs. The study was conducted on U.S. military veterans and demonstrated that Seroquel and other members of a new class of anti-psychotic drugs were linked to a higher risk of diabetes, but the risk of diabetes was greatest with Seroquel.

Seroquel may cause tardive dyskinesia--a condition characterized by uncontrollable muscle spasms and twitches in the face and body. This problem can be permanent, and appears to be most common among older adults, especially women.

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FDA Recalls

Food and Drug Administration--Recalls/Safety Alerts

Bakery El Monte Sinai Corp Announces Allergy Alert on Undeclared Eggs in Rainbow Cake
Bakery El Monte Sinai Corp., located at 100 A North Franklin Street in Hempstead, New York 11550, is recalling rainbow cake because it may contain undeclared eggs.
Hospira Announces A Nationwide Voluntary Recall Of One Lot Of Hydromorphone Hydrochloride Injection 1 MG/ML, (C-II) 1 ML Fill In 2.5 ML Carpuject, That May Contain More Than The Intended Fill Volume
Hospira, Inc. (NYSE: HSP), announced today it is initiating a voluntary user level recall of one lot of Hydromorphone Injection, USP, 1 mg/mL (C-II), 1 mL fill in 2.5 mL Carpuject, NDC 0409-1283-31, due to two reported complaints of a single Carpuject containing more than the 1 mL labeled fill volume. Opioid pain medications such as Hydromorphone have life-threatening consequences if overdosed.
NestlÃ© Purina Voluntarily Recalls Single Lot of Therapeutic Canned Cat Food Due to A Low Level of Thiamine (Vitamin B1)
NestlÃ© Purina PetCare (NPP) is voluntarily recalling one specific lot of its Purina Veterinary DietsÂ® OM Overweight Management canned cat food, available through veterinarians in the U.S. and Canada. This precautionary measure is being taken in response to one consumer complaint received by FDA.