Vioxx (rofecoxib) is a prescription drug belonging to a new class of non-steroidal anti-inflammatory drugs called COX-2 inhibitors. Traditional NSAIDs (ibuprofen and aspirin) block both COX-2 and COX-1 enzymes. However, COX-1 enzyme protects the lining of the stomach and blocking it can lead to stomach irritation. Vioxx works by blocking only COX-2 enzymes that cause inflammation characteristic to arthritis.
Vioxx is manufactured by Merck & Co. and is prescribed primarily to relieve symptoms associated with osteoarthritis. It can also be prescribed to relieve acute pain and to treat the pain associated with menstruation. Vioxx comes in 12.5mg and 25mg tablets or in liquid form and is taken orally.
Osteoarthritis
Approximately 15 million Americans suffer from the most common type of arthritis, osteoarthritis. Also known as degenerative arthritis, osteoarthritis occurs when cartilage begins to break down, eventually leading to the loss of cartilage in the joints. This causes joint pain, swelling, and friction between the bones
Osteoarthritis occurs most often in the hips, knees, feet, hands, and spine. There are two types:
Primary osteoarthritis - the most common type of osteoarthritis. Although there is no known cause of primary osteoarthritis, it is related to aging.
Secondary osteoarthritis - is caused by diseases or conditions such as obesity, diabetes, gout, hormone disorders, or repeated trauma to the joints.
Vioxx is prescribed to treat the pain and inflammation associated with osteoarthritis. It blocks the COX-2 enzymes that cause inflammation in the joints.
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Vioxx

